Abstract:
Vaginal contents - vaginal secretion - this is a serous vascular transudate, a secret of
the glands of the mucous membrane of the canine of the cervix and large glands of the vagina
front, of the leukocytes and of the epithelium of the corpus luteum [1]. The main chemical
composition of the vaginal secretion is water, inorganic salts, proteins (albumins,
immunoglobulins), carbohydrates, fatty acids, urea, lysozyme [2, 3, 8]. Physiological
maturation of epithelial cells, accumulation of glycogen in them and securing the acidity of
the vaginal secretion are affected by estrogen.
To the protective mechanisms of the vagina are physiological white, the normal
amount of which per day is up to 2 mg; A normal microflora of the vagina is present in the
form of lactobacter bifidobacteria, which compete with the vaginal microflora for glycogen
and create an acid medium. A key factor is the so-called "colonization resistance of the
vaginal secretion," which includes the protective agents that enter humoral pathway here and
are produced by local lymphoid tissue (IgA, IgM, IgG, lysozyme, a-lysines, complement,
secretory IgA, etc.), bactericidal compounds hydrogen peroxide, lactic acid), cells of the
immune system (leukocytes, macrophages, T- and B-lymphocytes) [4, 5, 6].
The purpose of the work was to study cellular and humoral indices at normal norms
and at different levels of dysbiosis.
