Abstract:
Vaginal bacterial dysbiosis is evident by the progressive growth of obligate and optional
anaerobic bacteria, myco- and ureaplasmas and fungi against the background of a sharp decrease in
the number of lactobacilli.
The aim of those work was to establish prognostic factors and the risk of bacterial dysbiosis development according to the vaginal normobiota indicator based on the comprehensive analysis of
the state of systemic and local immunity and hormonal regulation. As conclusions, with bacterial
dysbiosis the pathological regulatory hormonal-immune system is formed, which contributes to the
vaginal dysbiosis progression. In accordance with this, dysbiosis can be considered as a dysregulatory
pathology, and the identified indicators of the “interleukin cascade” as its markers.
