Видання іноземною мовою. Кафедра фармацевтичної хімії та технології ліків: Recent submissions

Now showing items 1-20 of 137

Research of the system of individual-typological features of personality in managers

Lobasyuk, B. A.; Savostin, A. P.; Bodelan, M. I.; Zamkovaya, A. V.; Stoyanov, O. M.; Лобасюк, Б. А.; Савостін, А. П.; Боделан, М. І.; Замкова, А. В.; Стоянов, О. М. (2024)

Using Benton’s tests, pictograms, and the Minnesota multi-aspect personality questionnaire (MMPI), aspects of mental activity were studied in managers and in mentally healthy individuals. Relations formed between test ...
Current state and prospects оf medicinal plants use and development of phytotherapeutic agents

Zamkovaya, A. V.; Ammari Abdelhak; Es Salmi Younes; Sherti Mohammed (2024)

Medicinal plants have a long history in medicine, being the basis for the treatment of many diseases for thousands оf years. Today, with the growing demand for natural remedies and growing concerns about the side effects ...
Solubility and hydrolysis of ammonium hexafluorosilicates as potential pharmaceuticals (a review)

Gelmboldt, V. O.; Гельмбольдт, В. О. (2024)

This review analyzes and systemizes results from publications on the solubility and hydrolysis of ammonium hexafluorosilicates (AHFS). These inorganic compounds have a variety of technological applications and have been ...
Biological activity of 3-hydroxymethylpyridinium hexafluorosilicate monohydrate and 4-hydroxymethylpyridinium hexafluorosilicate as candidates for anticaries agents

Gelmboldt, V. O.; Khromagina, L. M.; Nikitin, O. V.; Fizor, N. S.; Гельмбольдт, В. О.; Хромагіна, Л. М.; Нікітін, О. В.; Фізор, Н. С. (2024)

The aim of the study. Determination of the biological activity of new compounds – 3-hydroxymethylpyridinium hexafluorosilicate monohydrate (I) and 4-hydroxymethylpyridinium hexafluorosilicate (II), which we synthesized ...
Arterial hypertension and comorbidity: state of the art

Borysiuk, I. Yu.; Kovpak, A. V.; Fizor, N. S.; Zamkovaya, A. V.; Rhilа, Firdaose (2024)

Arterial hypertension (HTN) is frequently associated with comorbid diseases. Hypertensive patients commonly have one or several co-existent pathologies. The most frequent ones include diabetes mellitus, metabolic ...
Anxiolytic Properties of Derivatives of 1-Methoxycarbonylmethyl-3-Arylamino-7-Bromo-5- Phenyl-1,2-Dihydro-3H-1,4-Benzodiazepin-2-one

Andronati, S. A.; Karaseva, T. L.; Zamkovaya, A. V. (2017)

TSPO receptors are peripheral benzodiazepine receptors (PBDRs). Unlike central benzodiazepine receptors (CBDRs), PBDRs (TSPO receptors) are widely presented in organs and tissues of animals and humans; these receptors are ...
Лиганды 5-НТ1А и D2 рецепторов – N-(арилпиперазинил)бутилимиды бицикло[2.2.1] гент-5-ЕН-эндо-эндо-2,3-дикарбоновой кислоты и их нейротропные свойства

Андронати, С. А.; Карасева, Т. Л.; Замковая, А. В.; Соболева, С. Г.; Бойко, И. А.; Касьян, Л. И.; Цимбал, Д. И.; Andronati, S. A.; Karasyova, T. L.; Zamkova, A. V.; Soboleva, S. G.; Boyko, I. A.; Kasyan, L. I.; Tsimbal, D. I.; Андронаті, C. А.; Карасьова, Т. Л.; Замкова, А. В.; Соболева, С. Г.; Бойко, І. А.; Касьян, Л. І.; Цимбал, Д. І. (2013)

Відомо, що гетарил(арил)піперазини володіють важливими нейрофармакологічними (анксіолітичними, антидепресивними, нейролептичними та ін.) властивостями. У розвитку досліджень взаємозв’язку між структурою та властивостями ...
Производные [(N-арил)пиперазинил] бутилпиримидинов, обладающие нейротропными и актопротекторными свойствами

Андронати, С. А.; Соболева, С. Г.; Замковая, А. В.; Карасёва, Т. Л.; Ракипов, И. М.; Цимбал, Д. И.; Андронаті, С. А.; Соболєва, С. Г.; Замкова, А. В.; Карасьова, Т. Л.; Ракіпов, І. М.; Цимбал, Д. І.; Andronati, S. А.; Soboleva, S. G.; Zamkova, А. V.; Karasyova, Т. L.; Rakipov, I. М.; Tsymbal, D. I. (2016)

Синтезированы потенциальные лиганды 5-НТ1А рецепторов – арилпиперазины, содержащие в качестве терминальных фрагментов остатки тетрагидропиримидинов, соединения (1-6) и дигидропиримидина (7). Структуры соединений 1-7 были ...
Manifestations and treatment of atopic dermatitis in children

Kovpak, A.; Tsisak, A.; Eberle, L.; Zamkovaya, A.V.; Dabagh, N. (2024)

Atopic dermatitis is one of the most common allergic diseases that manifests itself in a severe form, affecting the skin. The disease is genetically determined and, unfortunately, is chronic. The manifestations of atopic ...
Changes in indicators of fibrinolysis and proteolisis in rats with spontaneous hypertension during treatment with ramipril

Chopiak, V. V.; Kovpak, A. V.; Pastryk, T. V.; Mishchenko, I. V. (2023)

The article concerns investigation of the state of proteolytic and fibrinolytic activity in rats SHR series with ramipril treatment. The study found that SHR rats a reduction process fibrinolytic activity, and after treatment ...
A year of life with an electronic prescription for vacation of antibiotics: study of opinions of pharmacy employees

Kalko, K. O.; Borysyuk, I. Yu.; Kovpak., A. V.; Калько, К. О.; Борисюк, І. Ю.; Ковпак, А. В. (2023)

The aim of this work was to distinguish the positive and negative aspects of the sale of antibiotics based on a respective survey of pharmacy workers (as of 30.08.2023, 50 respondents from different regions of Ukraine), ...
Study of possible sex features of ramipril and candesartan treatment under experimental arterial hypertension in rats

Tsubanova, N.; Kovpak, A.; Zamorskyi, I. (2022)

The article presents the results of a preclinical study of ramipril and candesartan in an experimental group of hypertensive rats of different sexes. Antihypertensive therapy was performed for 21 days. The drugs were ...
Types of off-lable drug use and informed consent doctrine when prescribing them

Drogovoz, S. M.; Khomenko, V. M.; Krynychko, V. V.; Barus, M.; Kovpak, A.; Ostapets, M. O.; Artiukh, T. O. (2021)

Today, medicine does not have a sufficient arsenal of drugs for the personalized treatment of cancer, neurological, psychiatric, pediatric patients, HIV-infected patients. An important aspect of informed consent when ...
Chronopharmacological studies of the hepatoprotective activity of silymarin under experimental toxic hepatitis in rats

Kalko, K.; Mishchenko, O.; Drogovoz, S.; Gerush, O. V.; Kovpak, A.; Gorna, O. I.; Bondareev, E. V.; Hainiuk, M. B. (2021)

Silymarin – a complex preparation of bioflavonoids of milk thistle, which contains silibinin A, silibinin B, silocristine, silidianin, isosilibinin A, isosilibinin B, isosilicristin, taxifolin. Chronopharmacological ...
Changes in lipid peroxidation activity in rats with congenital hypertension during candensartan treatment

Chopiak, V. V.; Kovpak, A. V.; Pastryk, T. V.; Mishchenko, I. V. (2023)

The article is devoted to the study of the peculiarities of the state of free radical peroxidation of lipids in rats with congenital arterial hypertension in the treatment of candesartan. In the test, it has been established ...
Development of the composition and technology of the anti-inflammatory gel for the relief of symptoms in diseases of the musculoskeletal system

Zamkovaya, A. V.; Drijad (abo Rabia), Hitam; Molodan, Yu. O. (2024)

Today, millions of people suffer from inflammatory diseases of the musculoskeletal system. At the same time, they are usually prescribed non-steroidal anti-inflammatory drugs, which usually relieve pain and inflammation, ...
Hexafluorosilicates: new antimicrobial agents to overcome antibiotic resistance

Bohatu, S. I.; Shyshkin, I. O.; Lytvynchuk, I. V.; Gelmboldt, V. O.; Guenther, S.; Rozhkovskyi, Ya. V. (2024)

The WHO Global Oral Health Status Report (2022) estimated that oral diseases affect close to 3.5 billion people worldwide, with 3 out of 4 people affected living in middle-income countries. Aim: Study of antibacterial ...
Study of propolis and wax moth extract as a preventive and therapeutic means for some diseases

Lakhmanyuk, Y. R.; Bodnarіuk, N. V.; Ustianska, O. V.; Eberle, L. V.; Tsisak, A. O.; Gritsuk, O. I.; Ulizko, I. V.; Лахманюк, Ю. Р.; Боднарюк, Н. В.; Устянська, О. В.; Еберле, Л. В.; Цісак, А. О.; Грицук, О. І.; Улізко, І. В.; Лахманюк, Ю. Р.; Боднарюк, Н. В.; Устянская, О. В.; Эберле, Л. В.; Цисак, А. А.; Грицук, А. И.; Улизко, И. В. (2024)

The paper presents an analysis of the literature data of the last decade on the clinical use of such apiproducts as propolis and wax moth extract as therapeutic and prophylactic agents. Interest in apitherapy and its ...
Optimization of extraction conditions for separation of flavonoids from the fruits of Maclura pomifera

Kobernik, A. О.; Tsisak, A. А. (2021)

The aim of this work was to optimize the extraction of samples of a fruit pulp with the purpose of increasing the yield of the final product – flavonoids. The methods of extraction are maceration for 30 days under ...
Pd(II)–Cu(II) compositions fixed on dispersed silica from ammonia solutions for carbon monoxide oxidation with air oxygen

Kiose, T. O.; Rakytska, T. L.; Holubchyk, K. I. (2023)

The samples of dispersed silica, tripoli from the Konoplyansky deposit, were used in this work. Pd(II)–Cu(II) compounds fixed on dispersed silica for the oxidation of carbon monoxide with air oxygen were obtained by ...

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Видання іноземною мовою. Кафедра фармацевтичної хімії та технології ліків: Recent submissions

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