This paper presents the results of the analysis of the relationships between the enzyme activity of the antioxidant system (AOS) and the nature of the development of the tuberculous process. A simultaneous study of the enzymatic activity of the various components of the AOS and the carbonyl groups in the peripheral blood was conducted in order to determine the changes in the oxidative stress during the anti-TB treatment. An inverse correlation between these indicators was established: the increase after two months of therapy of the level of antioxidant enzymes’ activity, which was reduced before the start of the treatment (p <0,05), along with the reduction of the initially elevated levels of the protein carbonyl groups in tuberculosis patients with destruction of the lung tissue and without it points at a certain recovery in the antioxidant defense system.
