The work deals with the role of lipid peroxidation defence in lungs of guinea pigs during experimental bronchial asthma (EBA) with adrenaline myocardial damage (AMD) on the 1-st, 4-th, 18-th and 25-th days. Results of investigations showed that on all stages of EBA with AMD development content of lipid peroxidation products (malondialdehyde and diene conjugates) increase, in this time on the 1st and 4th days activity of superoxide dismutase, catalase and glutathione reductase in lungs are increased with conseqently decreasing on the 18-th and 25-th days of experiment before treatment.
Using corvitin leads to decreasing of lipid peroxidation products content and increasing of antioxidation defence enzymes during EBA with AMD.