FEATURES OF BIOLOGICAL MECHANISMS OF POLYOLS

The study of the danger degree of chemical factors is based on a large range of research, among which it is obligatory to establish the characteristics of their biological action. Of particular importance is the definition of toxicokinetic and metabolic criteria for assessing the toxicity of xenobiotics, their influence on the antioxidant system of the body, which was the aim of this study. The basis of the mechanism of biological action is polyoxypropylene stimulation of lipid peroxidation, a violation of oxidative-reduction processes in the body of warm-blooded animals. General toxic effect of substances is characterized by liver and kidney dysfunction — organs that play a leading role in the detoxification of poisons.