“Onium” hexafluorosilicates as new potential caries protective agents

Abstract

In recent years, the possible usage of ammonium hexafluorosilicate (AHF) as caries-protector and hyposensitive agent in the practice of dentistry was demonstrated. According to silica, as a product of hydrolysis of AHF, acts as a non-trivial catalyst promoting the deposition of calcium phosphate or fluorapatite from saliva; silica is present in sediment that is formed on the dentin surface, thus providing prolonged dentin tubule occlusion. It is supposed that the other "onium" hexafluorosilicates, for example, with bioactive heterocyclic cations must have similar effect. In present communication we describe some results of synthesis, the study of the structure and properties of “onium” hexafluorosilicates – the fluoride containing salts with heterocyclic cations, exhibiting antibacterial, anti-inflammatory and sialagogue activity, as new potential caries protective agents.