Platelet-rich plasma enhances regeneration of the affected skin in case of experimental dermatitis

Abstract

Dermatitis is an urgent problem in modern medicine. At the same time, classic treatment of the deep dermatitis with the affection of the hair follicles is not efficient. Recently, great attention is paid to the use of platelet-rich plasma (PRP) which is effective in ulcerative lesions of the lower extremities treatment, healing of postoperative wounds etc. Therefore, the aim of the research was to study the impact of PRP on the regeneration of the skin of mice after induced contact dermatitis. The conducted studies have shown PRP promotes reparative regeneration of the skin, thus preserving the morphological properties of tissues and organ in general. This is provided with a number of growth factors that are released from platelets, enhancing proliferation of cellular elements in the affected area, as well as participate in the process of adaptation.