Ammonium hexafluorosilicates as potential anti-caries agents: influences of cation effects on the properties of salts

Abstract

Dental caries is one of the most important socially significant health problems in both industrialized and developing countries. In recent years, a high caries prophylactic efficacy of ammonium hexafluorosilicate (NH4)2SiF6 (AHFS) and ammonium hexafluorosilicates with biologically active cations (АHBAC) has been discovered. In the case of AHBAC using, there is a potential possibility of enhancing the anticaries effect of the fluorine-containing anion as a result of the contribution of the effects of cations, for example, anti-inflammatory and antibacterial effects. The purpose of this communication is analysis of the influence of ammonium cation effects on the physicochemical properties and biological activity of ammonium hexafluorosilicates in the context of their potential application as pharmaceutical agents.