Abstract:
Dental caries is one of the most important socially significant health problems
in both industrialized and developing countries. In recent years, a high caries
prophylactic efficacy of ammonium hexafluorosilicate (NH4)2SiF6 (AHFS) and
ammonium hexafluorosilicates with biologically active cations (АHBAC) has been
discovered. In the case of AHBAC using, there is a potential possibility of enhancing
the anticaries effect of the fluorine-containing anion as a result of the contribution of
the effects of cations, for example, anti-inflammatory and antibacterial effects. The
purpose of this communication is analysis of the influence of ammonium cation effects
on the physicochemical properties and biological activity of ammonium
hexafluorosilicates in the context of their potential application as pharmaceutical
agents.