PECULIARITIES OF DIAZEPAM EFFECTS UPON PENICILLIN-INDUCED EPILEPTIC ACTIVITY IN RATS UNDER CONDITIONS OF CEREBELLAR ELECTRICAL STIMULATIONS

Effects of diazepam administration (0.5; 1.5 mg/kg, i. v.) upon epileptic generalized activity induced in rats with sodium salt of benzylpenicillin solution administration (300 000 IU/kg) were investigated in acute experiments. It was shown that under conditions of electrical stimulations (100–300 Hz, 20 trials) of caudal parts of cerebellar vermis (flocculus and nodulus) diazepam caused more pronounced foci power reduction in comparison with it’s administration without stimulations.