ERYTHROCYTE LIPID PROFILE, PEROXIDATION STATUS OF LIPIDS, ANTIOXIDATION AND THIOL-DISULFID SYSTEMS OF BLOOD PLASMA IN YOUNG MEN WITH ARTERIAL HYPERTENSION

Erythrocyte lipid profile, peroxidation status of lipids (POL), antioxidation (AOS) and thiol-disulfide systems of plasma were studied in men of 18–35 years old with high normal blood pressure and the 1st grade of arterial hypertension in dependence on hereditary predisposition to hypertension and in 30 healthy men of the same age. Decreasing level of free fatty acids and phospholipids, increasing contants of cholesterol esters and the cholesterol/phospholipids ratio were revealed in the patients with hereditary predisposition to hypertension (HPH) in comparison with healthy men and patients without family anamnesis of hypertension. The activation of POL in plasma was revealed in the young men with high normal blood pressure and the 1st grade of arterial hypertension independently on family anamnesis of hypertension. AOS status in plasma depended on hereditary predisposition to hypertension.