INFLUENCES OF MAGNESIUM SALT OF GERMANIUM BIPHOSPHONATE ON MYOCARDIUM MITOCHONDRIAS ATP-ases ACTIVITY AT EXPERIMENTAL MYOCARDIAL DYSTROPHY

The article presents results of an experimental research of the activity Mg2+– and Na+-, K+-АТP-ase in the mitochondrias of cardiac muscle at the development of myocardial dystrophy and its prevention and medical treatment by a new biologically active substance — derivative of germanium biphosphonate with magnesium (MIGU-6). It is established that the administration of MIGU-6 with a medical purpose substantially diminished the term of renewal of the АТP-ases activity. If arbitrary renewal of activity of enzymes developed on the 14th day only, at medical introduction of studied substance it developed already on the 5th day, that is almost 3 times as much, that is very important for clinical practice.