The goal of our work was the investigation of Silybum marianum L. Gaerther and Calendula officinalis L. extracts’ effects on the hydrolysis and transport of the carbohydrate and protein derivatives with the different level of polymerizing and their mixtures.
It was showed that including of those plants extracts into the incubation medium does not change rate of the 10 mmol/l free glycine transport, but inhibits transport of the 10 mmol/l free glucose by 40 and 50 % accordingly. Due to incubation the small intestine fragments in the mixture of 10 mmol/l glucose and 10 mmol/l glycine the calendula extract inhibits the glucose transport by 38 % simultaneously with stimulation of the glycine transport by 45 %.
Thus, in this model condition extract of calendula inhibits active transport of both free glucose and M-glucose, and active transport of these substrates in the presence of the free and “peptide” glycine accordingly.