THIOL-DISULPHIDE SYSTEM STATE IN PATIENTS SUFFERING FROM CHRONIC PANCREATITIS UNDER CONDITION OF COMPLEX LAPAROSCOPIC MINIINVASIVE TREATMENT

Laparoscopic treatment of chronic pancreatitis complications (42 patients) causes less pronounced deteriorations in the functional state of thiol-disulphide system of the blood in comparison with traditional treatment (25 patients). A relatively higher level of thiol groups along with less significant increasing of disulphide groups was kept both in non-protein and protein fractions of blood and in blood serum. The usage of pentoxyphyllinum in the complex therapy (0.1–0.2 g, i. v. daily during 7 days) significantly improved indices of functional state of the thiol-disulphide system in postoperative period (22 patients).