The content of lactate, malate and pyruvate, lactate / pyruvate, malate / pyruvate and NАD / NАDН, NАDP / NАDPН ratios in organs of rats at oral introduction different cultures of spirulina have been determined. It has been revealed that the content of lactate, malate and pyruvate in rat organs changes to different degree and ways. The ratio of NAD / HADH increased as a rule, and the ratio of NАDP / NАDPН decreased. These changes indicate to carbohydrates aerobic metabolism activation and oppression of lipogenesis.