PATHOMORPHOLOGICAL ASPECTS OF THE PERIPHERAL IMMUNE SYSTEM DURING THE EXPERIMENTAL TOXIC HEPATITIS

Immunohystochemical research of basic populations of immune cells located in the spleen was carried out in the rats at injections of heptral on the background of the experimental acute toxic hepatitis (ATH) caused by carbon tetrachloride. It was shown that injections of heptral decrease complement’s C3-fractions. They increase amount of plasmocytese and macrophages, helper-suppressor’s index, which approaches to the normal condition. Received results show more balanced relations between basic chains of immunogenesis during ATH and using heptral at the same time.