MONOCYTES PHENOTYPE PECULARITIES IN PATIENTS SUFFERING FROM CHRONIC RENALS DISEASE IN CONNECTION WITH ENDOTHELIUM CONDITION

The investigation was performed on monocytes and circulating endothelial cells (CECs) in 40 patients with chronic kidney disease (CKD), 24 patients with arterial hypertension and 12 healthy persons. Increased numbers CECs and CD14+/CD16+ monocytes were presented in peripheral blood of both patient groups. But patients with CKD showed more pronounced elevation of this parametres. Abnormalities of CECs and monocytes may be considered as a contributing factor for atherosclerosis in CKD. Determination of CECs and CD14+/CD16+ monocytes number in patients with CKD may have important diagnostic value.