Maintenance of blood in the liquid state and its preservation within the vascular bed is normally determined by the equilibrium systems responsible for thrombus formation on the one hand and the blood flow — on the other hand. In the process of hemostasis liver is of great importance: Pathology of hepato-biliary system, resulting in its functional disability, affecting all components of hemostasis. The main pathogenetic mechanisms of disorders of hemostasis in liver disease are thrombocytopenia, endothelial damage, impaired protein-synthetic function.
