CUMULUS CELLS DNA DAMAGE UNDER CONDITIONS OF EXPERIMENTAL IMMUNE DESTRUCTION OF OVARIES IN MICE

Evaluation of integrated genome integrity, the ratio of DNA material in the “head” and “tail” of the comet, as an indicator of the functioning oocyte cumulus cell genome, gives reason to believe that immune ovarian failure as well as cytokines can alter the activity of gene expression and processes damage and repair, manifested as double-stranded DNA.