CLINICAL AND MORPHOLOGICAL CHARACTERISTICS OF THE FETOPLACENTAL COMPLEX IN PREGNANT WOMEN WITH IRON DEFICIENCY ANEMIA AGAINST A BACKGROUND OF CHRONIC UROGENITAL INFECTION

The aim of the study was to evaluate the clinical peculiatities of pregnancy in women with iron deficiency anemia against a background of chronic urogenital infection.

There were examined 150 pregnant women with manifestations of iron deficiency. All of them were divided into 3 clinical groups: the patients with verified urogenital infection (n=50), the women with chronic pyelonephritis (n=50), who were treated according to an ordinary algorithm, the women with chronic pyelonephritis and urogenital infection (n=50), who had pre-gravidar preperation and complex treatment.

Pregnant women with chronic urogenital infections had manifestations of iron deficiency anemia in 83.0% of cases. Chronic pyelonephritis led to a profound deficit of serum iron up to (8.78±1.70) mmol/l with ferritin level (7.2±0.2) mg/l, which is below the control values (p<0.05).

Immaturity of the placenta, pronounced hemodynamic disorders and invalution dystrophic processes were diagnosed in 10% of patients with anemia and pyelonephritis. Compensatory-adaptive reactions are formed by terminal villi and vesicles hyperplasia and formation of cyncytiocapillar membranes.