PECULIARITIES OF MAXIMAL ELECTROSHOCK SEIZURES UNDER CONDITIONS OF CEREBELLAR TRANSCRANIAL STIMULATION WITH CONSTANT CURRENT IN RAT

The net shortening of tonic flexion (by 27.6–30.3%, p<0.05), tonic extension (by 29.6–36.4%, p<0.05) as well as duration of clonic seizures (by 25.0–35.1%, p<0.05), and stretching reflex duration by two times (p<0.05) was registered when maximal electroshock seizures were induced after transcranial cerebellar stimulation with anode (600 mcА, 15.0 min). Such effects were seen during first two hours of poststimulative period. The analogous cerebellar stimulation with cathode also induced the shortening of tonic extension — the effect observed in 1.0 up to 10th hour from the moment of stimulation. During the early poststimulative period (up to 0.5 h from the moment of stimulation) cathode-induced effects significantly exceeded such ones induced with anode stimulation and were opposite with their sign pertained to control ones.