ASSESMENT OF RISK FACTORS OF ATOPIC DERMATITIS IN CHILDREN

The study was aimed on the monofactorial analysis of risk factors of atopic dermatitis (AD) in children and evaluation of their statistical significance. 110 children from 2 month to 12 years with atopic dermatitis were involved in the study. The control group consists of 50 healthy children with a similar gender and age. The monofactorial analysis was performed by means of the statistical software STATISTICA 6 and included the calculation of the odds ratio and its 95 % confidence interval and the attributive risk. The significance of the risk factors for atopic dermatitis development in children was estimated by “Feature Selection and Variable Filtering” method of the Data Mining module. Hereditary factors, peculiarities of the course of the perinatal period, environmental factors, and factors related to the child and mother’s nutrition were studied. Results of the study showed that the greatest statistical significance in our study was hereditary factors and nutritional factors, associated with the role of food allergy as a trigger and cofactor for the development of AD in children.