MODERN ASPECTS OF PATHOGENESIS OF FETAL DISTRESS IN PREGNANT WOMEN WITH HYPERHOMOCYSTEINEMIA (review)

One of the most important areas of modern medicine is the antenatal protection of the fetus and newborn child.

According to the literature, the pathogenesis of fetal distress characterize chronic lack of oxygen and is associated with the activation of oxidative modification of proteins and lipids, an imbalance in the system of vasoconstrictors — vasodilators and other metabolic disorders in fetoplacental system.

Over the past decade has increased the frequency of extragenital and congenital abnormalities, reduced fertility. It remains a high perinatal morbidity (46.3–78,00 ‰), due to a complication of pregnancy hyperhomocysteinemia and narodzhenyaya functionally immature child with developmental delay in the case of premature birth.

All this dictates the need for in-depth study of the state of hemodynamics in the mother-placenta-fetus, pathogenesis, clinical manifestations, diagnosis of fetal distress when hyperhomocysteinemia in pregnancy, nd further improve the management practices of pregnancy, childbirth and antenatal protection of the fetus in such cases.