METABOLIC INFRINGEMENTS AND THEIR PHARMACOLOGICAL CORRECTION AT THE COMBINED ACTION OF γ-IRRADIATION AND PSYCHOEMOTIONAL STRESS

It has been established, that γ-irradiation and psychoemotional stress essentially influence metabolic processes in the liver that is shown by discoordination activity of methylation and ADP-ribosylation reactions, reduction of the cyclical nucleotides contents. Heptral and germamide course introduction considerably reduced negative action of these factors. Combinative application of the given preparations practically kept investigated parameters of liver metabolism at a level of control values.