The treatment of 56 patients suffering from IHD, instable stenocardia of progressing current and essential hipertension of II degree. The patients are divided into 2 groups. 1st group (25 patients) received (with hypotensial purpose) diroton 5 mg, then 10 mg; stamlo 5 mg, then doze of stamlo was increased up to 10 mg.
As a result of supervision was established, that the AP both systolic, and dyastolic is authentically reduced at application of diroton, but hypotensial effect at combined application of dirotone and stamlo is more expressed. Also was established, that the application of dirotone and stamlo promotes circade rhythm normalization.