Cytogenetic studies of chromosomal damage in cosmonauts’ blood lymphocytes showed a statistically significant increase in the yields of radiation-dependent chromosomal aberrations (dicentrics and centric rings). The influence of antiorthostatic hypokinesia (simulated weightlessness) results in an increase in the frequency of acentric aberrations. Psycho-emotional stress (long-term isolation) is found to lead to increased yields of acentric fragments and chromatid aberrations. It is supposed that each space factor under consideration can induce chromosome damage of a certain type.
