PROTEOLYSIS-INHIBITORY AND PROOXIDANT-ANTIOXIDANT SYSTEMS IN PATIENTS SUFFERING FROM DIABETIC RETINOPATHY

The general proteolytic activity (GPA), content of trypsin inhibitors (TI), concentration of malonic dialdehyde (MDA) and activity of antioxidant ferments (CAF) was determined in blood serum of 64 patients with insulin-independent diabetes with display of retinopathy. Determined that levels of GPA, TI, CAF had increased and MDA — decreased. The ratio of TI/GPA increases slightly but coefficient of CAF/MDA increases significantly that is evident about the expressed activation of protective processes in the patients with diabetes.