The results of the study of the influence of the pathological levels of antiphosholipid antibodies on the system of hemostasis in pregnant women with the hestosis are represented.
The clinic-laboratory inspections were carried out in I, II and III trimesters of the pregnancy of 28 pregnant women with the physiological course of pregnancy and 70 pregnant women with gestosis of a different degree of severity. By the hemostasiologic researches the increasing hypercoagulation in a plasma part, the activation of the aggregate activity of the thrombocites and the increase of markers levels of the thrombophilia were detected. The increasing thrombophilia condition of the system of hemostasis results in the increase of symptoms of the gestosis severity. Considering the presence of АPА as the acquired thrombophilia, it is necessary to carry out the researches on the presence of АPА and the latent thrombophilia with the manifestation of the first gestosis symptoms. In case of the detection of APA it is necessary to carry out therapy correcting the system of hemostasis.