In chronic experiments on Wistar rats it was shown that repeated administrations of corazol in subthreshold dosages (30.0 mg/kg, i. p.) was followed by the appearance of spike-wave (SW) bursts of discharges. Duration of such bursts as well as common period of their registration were prolonged in the course of epileptogen administrations. High-frequency (100) Hz electrical stimulation (ES) of palecerebellar cortex induced the reduction of the duration of SW-bursts along with the reduction of life- span of bursts. Low–frequency (10 Hz) ES was resulted in timely developed effect of decreasing of the duration of SW bursts.
