The study of [3H]-amixin excretion from the mice organisms at two methods of the oral repeated injection had shown, that during the course of experiment, the preparation and its metabolites were being excreted at a rather slow rate. The general process is mainly determined by the parameters of urine excretion of the [3H]-products: at the repeated injection — up to 40 %, and about 15 % of the radioactive material injected upon the once injection, basing on the repeated injection of the nonradioactive preparation; and with feces — about 16 and 10 % of the total radioactive material, respectively. Amixin is the organism’s monooxygenase system activity inhibitor, the change of its excretion parameters, during the prolonged injection of the preparation changes the rate of its biotransformation, slowing the process of its metabolites from the organism. It might be recognized during the prolonged usage of the preparation.
