3Н-amixin excretion processes from the mice organism after single intravenous and per. os. administration has been carried out. The research results have shown, that the drug and its metabolites are slowly eliminated from the organism of experimental animals and independently on the way of introduction about 60% of the dose are eliminated. The equal efficacy of excretion with urea and feces and monoexponentiality of excretion processes is characteristic for the excretion of the examined substance. The Manghelsdorf’s method, which allows carrying out an estimation of kinetic parameters of drugs elimination from the organism, has been developed.
