MORPHOLOGICAL CHANGES IN THE RATS’ LIVER UNDER THE ACTION OF DICHLORDIPHENYLETHYLEN

Morphohistochemical researches of the rats’ liver after DDE introduction are carried out. It was established, that in liver cells hydropic dystrophias resulting in destructions and losses of a part of hepatocytes develop. One of the toxic effects of DDE was the cell’s genetic apparatus damage and, as a results, the atypical mitosis forms formation. The compensative-reparative processes in the liver were sufficiently active and they were carried out exclusively by the way of hepatocytes mitotic proliferation.