Kindling induction via corazol subthreshold administrations (35,0 mg/kg, i.p.) was followed by enlargement of active wakefulness phase (by 71,2 %), reduction of both slow-wave sleep and paradoxical sleep phases correspondingly by 37,8 and 39,8 %. The prolongation of the latent period of paradoxical sleep precipitation — by 44,2 % was also noted. Interferon (10,000 IU/kg, i. p.) induced the shortening of the latent period of sleep in intact rats by 37,5 %, while in kindled rats the shortening of the phase of active wakefulness by 22,0 % along with shortening of latency by 34,1 % and prolongation of total duration of paradoxical sleep by 17,7 % was registered.
