INFLUENCE OF THYMECTOMY AT THREE DAYS OF AGE ON THE BONE DENSITY IN MICE CBA/Ca

Influence of thymectomy at three days of age on the bone density have been studied in experiments on female and male CBA/Ca mice. Gravimetric method of femoral bone density measurement was performed. At the age of three days thymectomy leads to significant decrease of bone density in female and male mice, significant increase of number colony forming unit of fibroblast (CFU-F) and number colony forming unit of granulocyte/macrophage (CFU-GM) for female and male mice. The body mass of mice, the mass of adrenal glands, uterus, testis and level of sex gormons were significantly decreased.