Endothelium-dependent and dilatation effects of vinboron were studied on rat aorta fragments in the experiment. It was determined that vinboron produced stimulating effect on NO and NOS lewels resulting in persistent vasodilatating effect. Vinboron injection produce persistent and dose-dependent relaxation of rat aortic rings. Slow and gradual rehabilitation of muscle contractive strength was observed in the ends of aorta with intact endothelium while in endothelium-denuded rings of aorta that was much slower.
