The data on different cytokines mechanisms of action upon excitability of brain structures along with the neurochemical peculiarities of it’s action and behavioral deteriorations are in scope of the review. Those data which are in favor for the role of heightened level of cytokines in the neuropathological syndromes precipitation, namely epileptic syndrome and child cerebral palsy were analysed by authors. The conclusion was made that state of cytokine system might compose the pathogenetical basis for working out new approaches to the control of pathologically deteriorated excitability of neuronal populations.
