On the basis of examination of 62 patients it is revealed the different level of functioning of hypothalamo-hypophysial-adrenal system and depending on it hemodynamics systemic parameters changes, that characterizes the role of this system in chronic heart failure development. Interdependence between a condition of regional hemodynamics and a level of adrenocorticotrophic hormone and hydrocortisone is indicative of hormones action and on presence of specific receptors in those or other vascular pools. Lability and severity of heart failure are caused by the central mechanisms including — functioning hypothalamus and the anterior part of hypophysis.
