PEROXIDATION OF LIPIDS AND OXIDATIVE MODIFICATION OF LYMPHOCYTES MEMBRANES PROTEINS AT UROGENITAL CHLAMYDIOSIS

In lymphocytes suspension of patients suffering from urogenital chlamydiosis and practically healthy donors defined the level of LPO products and the degree of oxidative modification of proteins were defined. Na/K-and Ca-ATP activity were also estimated. It is shown, that in lymphocytes membranes of the patients with chlamydiosis the elevated level of both products of lipoperoxidation of PUFA and the modified proteins. Activation of Ca-ATP is noted. It is assumed that these changes can cause disorder in the immune system of the patients with urogenital chlamydiosis and lead to chronization of the pathological process.