The data of clinical studies are given concerning myoma diagnosis and treatment efficacy increasing through principally new approach with uterus body safening — using uterine arteries roentgenendovascular embolization that allow to preserve the uterus and reinduce the repoductive function. Additionally, authors investigated plasma levels changing of the cytokines and trophic factors — tumor necrosis factor-alpha (TNF-α), interleukin-1, interleukin-6, transforming growth factor (ТGF-1β) and granulocite-macrophage colonystimulating factor — in women with suspicious to myoma development. TNF-α and ТGF-1β plasma levels significant increasing were shown 1 month before the disease starting that was taken by authors as the disease earliests nonspesific diagnostical tool. No diagnostical criteria were useful for the earliest disease diagnosis.
