The correlation analysis of parameters of aspartate and alanine aminotranspherase, lactate dehydrogenase, creatin kinase, amylase, red and white blood, lipid, protein and carbohydrate metabolism, coagulogram in 1,776 patients, neuroendocrine status in 71, processes of lipid peroxidation — antioxidant system in 53 patients suffering from ischemic heart disease (IHD) and chronic heart failure (CHF). There estimated biochemical processes of proteins, fats, carbohydrates metabolism and a role of the enzymes, the liver, skeletal muscles in metabolism path ways, which cause compensation providing IHD and CHF, conjugated function of organs and systems for maintenance of compensation is revealed. Development of methods of the therapeutic influence directed on restoration of metabolism, in particular, in the liver and pancreas for the prevention of IHD and CHF development and treatment is considered necessary.
