The effect of 7-alkyl-8-piperazyno-3-methylxanthines, the visceral sensitivity nociceptors and the flogogenic inflammatory process course were examined for the first time. It was discovered that compound 3 reduces painful response to visceral stimulation of acetic acid nociceptors by an average 50.4%, and reduces development of flogogenic edema in rats’ feet by 48.4%. Thus, 7-alkyl-8-pyperazyno-3-methylxanthine is a promising group of organic substances and the subsequent synthesis and study of pharmacological activity in order to create a new non steroid anti-inflammatory drugs is appropriate.
