The results of complex investigation and treatment of 110 premenopausal patients with abnormal uterine bleedings caused by recurrent hyperplastic processes of endo- and myometrium were observed. In cases with mostly positive expression of ER and PR in endometrium we used levonorgestrel-releasing intrauterine system. Improving of diagnosis and treatment of hyperplastic processes of endo- and myometrium consists of complex using of transvaginal sonography, dopplerometry, hysteroscopy with cervical and uterus curettage with hystologic confirmation and estimated steroid receptors and proliferative profile of endometrium.
