THE EXPERIMENTAL SUBSTANTIATION OF THE USE OF THE OINTMENT CONSISTING PROPOLIS AT PERIODONTAL TISSUES PATHOLOGIES

The results of the experimental study of the therapeutic effectiveness of the ointment consisting propolis in laboratorial rats at the periodontitis are given. The indices of prooxidant (concenttration of malonic dialdehyde (MDA)) and antioxidant (activity of catalase) systems in blood serum and their ratio (index API) were studied. The considerable increase in contents activity of proteases and MDA, essential decrease in catalase activity, and index API, in particular, were determined in the rats with periodontitis. The application of the elaborated treatment ointment consisting propolis normalizes salivation, reduces activity of proteases, concentration of MDA and increases activity of catalase and antioxidant-prooxidant index (API).