There were investigated characteristics of the pain syndrome, quality of life and degree of affection of the knee joints in patients with osteoarthrosis in absence and presence of synovitis. 59 patients were examined, 19 men and 40 women, with the average age of (57.2±1.5). The clinical and laboratory-instrumental study was conducted including roentgenography of the knee joints in two projections with determination of the roentgenological stage by I. Kellegren, I. Lawrence with changes of M. Lequesne. The episodes of synovitis have been observed in 28 patients for 3 years. At the end of the observation the progressive affection of the joint was observed in 10 (32.3%) of 31 patients of the group without synovitis and in 15 (53.6%) of 28 patients with sinovitis. Thus, the group of the patients who had had synovitis for three years were reliably more frequently observed progressive affection of the knee joints.
