It was carried out clinical and genetical observations of 80 patients suffering from inflammatory bowel diseases (ulcerative colitis and Crohn’s disease). The hereditary form of ulcerative colitis was determined in 5 (9.4%) families and Crohn’s disease — in 4 (14.8%) families with using of pedigree analysis. It was shown that pathology of the musculoskeletal system among extraintestinal features of disease was significantly higher in patients suffering from Crohn’s disease to compare with ulcerative colitis (in sporadic and hereditary forms). Among the spectrum of extraintestinal symptoms the eyes pathology rate was significantly higher in patients with the hereditary form of ulcerative colitis as compared to sporadic form, and the frequency of skin pathology was significantly higher in patients with the hereditary form of Crohn’s disease as compared to the sporadic form.
