There were studied some peculiarities of metabolism of biogenetical amins and their predecessors under conditions of subacute experiment on white rats in 1/100 DL50 in case of influence of neonols and also the system of secondary neuromediators. There was established structural metabolic injury of mediator regulation of cellular units under influence of researched neonols. AF 9-12 has stronger influence on intracellular metabolism. The results of research of PAV influence on membranes and membrane processes allowed to draw a conclusion about membrantoxical influence of oxyethylized phenols derivatives.