Electrophoresis of pylocarpine hydrochloride to women with hypoestrogenemic type of the skin was followed by induction of stable type of response in 20.0% of patients (control group — 75.0%), quick unstable response — in 40.0% (control group — 20.0%), quick transient — in 30.0% (control group — 5.0%). Besides, in 10.0% patients postponed character of response was evident. Complex treatment with laser abrasion of the skin, pentoxyphylline and L-corargine caused positive therapeutic effects both on NO-depended and NO-independed vasodilatative responses.
