INCREASING OF ANTIEPILEPTIC ACTION OF DIAZEPAM CAUSED BY KETOGENIC DIET ON FOCAL MODEL OF EPILEPTIC ACTIVITY

The effects of rats experiments ketogenic diet usage (80% of lipids, 3.3% of carbohydrates and 16.7% of proteins) and diazepam (0.05 and 1.0 mg/kg, i. p.) of male Wistar upon penicillin-induced foci of epileptogenesis have been investigated under acute conditions. The precipitation of pronounced antiseizure effects after administration of diazepam in independent non-effective dosage (0.05 mg/kg, i. p.) in rats under ketogenic diet was described.