In experiments on Wistar male rats it was established that combined usage of reserpine (2.5 mg/kg, i. p., for three days) and immobilizing and electropain stress causes the appearance of duodenal and ulcers and increases tripsin, amylase activity along with the decreasing of the level of tripsin inhibiting factor in blood plasma. Administration of L-deprenyl (0.5 mg/kg, i. p.) and pentoxyphylline (50.0 mg/kg, i. p.) renders protective effect to appearance of stress-induced disturbances of the gastrointestinal tract.
